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PLoS ONE 9:e85885

NAD + centric mechanisms and molecular determinants of skeletal muscle disease and aging

Qu S, Qin T, Li M, Zhang S, Ye L, Wei J, et al

Educate the patient and their family/caregivers about sick day rules for managing diabetes during illness, emphasizing the importance of never eliminating insulin doses when experiencing nausea or vomiting

Besides being a potential source of more reactive free radicals via Fenton reaction, physiological generation of H 2 O 2 fulfills a second messenger role and can be transported across membranes by aquaporins, a family of proteins that act as peroxiporins (Sies, 2014)