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When patients were grouped according to the sum of risk scores, the OS rates were 100% in the low risk (score 0-1), 75% in the intermediate risk (score 2), and 14.3% in the high risk (score 3) group ( P =0.0018)

This discrepancy between studies was probably not due to significant differences in PK profiles as we observed similar l-glutamine exposure levels as reported in Ziegler et al., and l-glutamine T 1/2 in both studies is approximately 1 h

This is due to ABZ inhibiting CYP1A and CYP3A metabolic pathways involved in the metabolism of (R)-PZQ (182)

This is especially remarkable for very weak resonances (seen between 3 },\) since Fourier vectors in the frequency domain are not of equal length for various truncation levels of the total acquisition time T [9]