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La pathognie de cette anmie des affections chroniques du foie est complexe : dficiences multiples de l'rythropose, perturbations d'un cycle entro-hpatique, endotoxines microbiennes non dtruites par le foie Anmies macrocytaires plus rares, d'origine non lucide [modifier | modifier le code] Autrefois appeles anmies rfractaires , car rsistantes au traitement par la vitamine B 12 ou l'acide folique, elles sont dues une anomalie de l'ADN des cellules sanguines souches

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It works by mimicking the effects of a natural hormone called glucagon-like peptide-1, which helps regulate blood sugar levels in the body

Three times daily systemic (SC) treatment of DIO mice with 20 mg/kg of 5-amino-1MQ produced a progressive loss of body weight over the treatment period compared to controls (FIG