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Several large observational studies have reported associations between frequent or prolonged acetaminophen use during pregnancy and higher rates of neurodevelopmental disorders in children

Kedziora-Kornatowska K, Czuczejko J, Pawluk H, Kornatowski T, Motyl J, Szadujkis-Szadurski L, et al

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Meanwhile, M2 macrophages-derived extracellular vesicle (EVs) could also convert activated M1 macrophages into M2 macrophages through in situ macrophage reprogramming and producing a distinct protein expression pattern characteristic of anti-inflammatory M2 macrophages