methionine precursor glutathione Homocysteine metabolism and (GSH) synthesis. The Sulfur metabolism diagram. The essential

3 Brief description of important metabolic pathways 3.1 The tricarboxylic acid (TCA) cycle (also called Krebs cycle or citric acid cycle) The TCA cycle takes place within the mitochondrial matrix and is a central regulator of energy production by oxidation of acetyl-coenzyme A (acetyl-CoA) derived from the metabolism of carbohydrates (and more specifically from glucose-derived pyruvate), fatty acids as well as proteins ( 2 the reduced form of flavin adenine dinucleotide (FAD) -, which will enter the oxidative phosphorylation pathway to further generate energy in the form of ATP (Martnez-Reyes and Chandel, 2020)

Ethics declarations Conflict of interest Nicola McCarthy is an employee of Horizon Discovery

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

doi:10.1016/j.jacc.2017.10.024 Harrington, Jennifer et al

This makes sense given that glutathione works through ongoing metabolic processes rather than permanently altering melanin-producing cells