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Derry PJ, Kent TA (2017) Correlating quantitative susceptibility mapping with cognitive decline in Alzheimers disease

With high energy output from mitochondria comes higher free radical and ROS production and greater susceptibility to oxidative stresswhich is where glutathione comes in again.* The sirtuin SIRT3a longevity-related protein that requires NAD+ for proper functioningis also involved here, helping to maintain hearing during aging by promoting glutathione-mediated antioxidant defense systems

Selenium is a key mineral involved in the production of glutathione within our cells

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10.1021/acs.bioconjchem.4c00462 175 WangS.LiuY.SuM.WangY.WangW.WangW.et al (2024c)