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Then, using cultured human keratinocytes, different roles were established for Cu/Zn SOD and Mn SOD

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In human colorectal cancer cell lines, loss of proapoptotic protein Bax led to 5-FU resistance ( 2.1.2 Ferroptosis Ferroptosis is an iron-dependent, non-apoptotic method of cell death, induced by reactive oxygen species and an imbalance of intracellular lipid redox