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From the slopes, the kinetic rate constants k(observed fluorescence decay) were evaluated, and summarized in Table 2

Current guidelines recommend the elective repair of all symptomatic PEH, while in asymptomatic patients the indications to elective surgery must be balanced with the patients age and comorbidities [5]

When oxidative stress occurs within the skin layers, it can weaken this barrier

Tenaillon O, Skurnik D, Picard B, Denamur E

The protonation reaction results in the formation of peroxynitrous acid which undergo hemolytic cleavage to form nitrogen dioxide and hydroxyl radicals (Lobo et al., 2010)