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10.1038/s41573-021-00355-6 269

M.ElsamanoudyA

These effects were generally mild to moderate in intensity and were most frequent during the dose escalation period, becoming less common as participants remained on their maintenance dose

96 A functional decline was observed in aging T and B cells

Addressing these gaps, our meta-analysis systematically integrates data from a broader range of studies, applies rigorous inclusion criteria, and employs advanced statistical models to improve the reliability of the findings