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In BV2 microglial cell lines subjected to lipopolysaccharide (LPS)-induced neuroinflammation, both lactylation-mediated inhibition of p53 activity and direct knockdown of p53 protein can disrupt the control of the NF-B inflammatory signaling pathway, ultimately leading to abnormal expression of pro-inflammatory factors and M1 polarization of microglia [132]

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How viral infections cause neuronal dysfunction: a focus on the role of microglia and astrocytes

Bordi, M

You can review glutathione IV therapy options or schedule an appointment when it works best for you