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At the same time, cholinergic neurons are known to be involved in regulating cognitive functions including fear (Boskovic et al., 2018

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In addition, damage of the ER may cause a release of Ca 2+ that provokes its overload and subsequent mitochondrial damage, leading to increased ROS production (Fig

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Many phenolic acids are also known to suppress the NF-B pathway, thereby reducing pro-inflammatory cytokines in the tumor microenvironment and sensitizing cancer cells to immune attack (150)

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