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GHK-Cu: Gene Expression and Tissue Remodeling Tissue repair , collagen synthesis, and extracellular matrix remodeling Anti-inflammatory signaling through inhibition of TNF- and IL-6 expression [1] Copper ion delivery into cells, promoting antioxidant enzyme function and cellular respiration [2] 2

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Multinucleated myofibers are not well captured in the single-cell isolation protocol, so the abundance of myonuclei is underrepresented within the scRNA-seq dataset

Generally, these reactions occur during or shortly after treatment, and so, are easy to recognize