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(10) Studies have documented that IGF-1 signaling promotes fibroblast proliferation, collagen synthesis, and angiogenesisall critical components of wound healing

We demonstrate that the cancer-related truncated variants ASXL1 1-645 and ASXL1 1-591 retain BRD4 binding function, with ASXL1 1-645 showing an enhanced ability to recruit BRD4 to ASXL1-occupied promoter regions

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Oehlers SH, Cronan MR, Scott NR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS, Tobin DM

This results in sustained release, better tissue targeting, stronger mitochondrial protection, and improved redox balance