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Description

it is notably discovered in bones, tendons, ligaments, corneas and various interstitial connective tissues (64)

Wang D, Tang L, Wu Y, Fan C, Zhang S, Xiang B, et al

Vitamin B6 is crucial for the production of haemoglobin and, by participating in the production of antibodies, it improves the body's immunity

This interaction blocks Keap1s ubiquitin-dependent degradation of NRF2, stabilizing the protein and promoting its nuclear translocation and transcription of target genes, thereby forming a p62-Keap1-NRF2 positive feedback loop