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2022;55(6): e13246

Indeed, the ability of organisms to dispense with a Co requirement by replacement with alternative enzymes, and to conditionally express the B 12 -independent version as needed, is a widespread adaptation

Its targeted mechanism means fewer side effects compared to other growth hormone therapies

More importantly, although we have collated the evidence on the penetration of hepatokines into the BBB, variations in research approaches and indirect measurements introduce uncertainties