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Ingredients to Avoid in Acne Products Certain ingredients can aggravate your condition by worsening acne and inflammation

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However, significant challenges remain, including the synthesis of stable tripeptides with good tissue penetration, insufficient understanding of their mechanisms of action, the scarcity of studies in larger animal models and human trials, and the lack of direct head-to-head comparisons with larger peptides [75, 95]

Munc18-1 deficient mice were generated as described previously (de Vries et al., 2000)