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Extensive research has established glutathione peroxidase 4 (GPX4) as a critical regulator in the pathogenesis of multiple pathological conditions, including osteoarthritis 35 ,cancers 47 , and liver disease 48

J Dermatol Sci 61(1):2331

Oral consumption of sulforaphane precursor-rich broccoli supersprouts decreases serum levels of advanced glycation end products in humans

They show why the compound has become important in metabolic science and why ongoing trial results are being watched closely

When we look at specific goals like skin health, eye protection, or brain function, other compounds like astaxanthin or melatonin may actually offer higher levels of antioxidant activity in certain environments