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Lapatinib ditosylate can activate the Nrf2/GPX4/GSH axis and inhibit the accumulation of 4-HNE, thereby alleviating motor dysfunction and neuropathological damage (266)

Vera E, de Bernardes Jesus B, Foronda M, Flores JM, Blasco MA (2013) Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity