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But our results did not show any association between serum B 12 concentration and MS, disease age of onset, or clinical disability which is similar to some,[9,10] but in contrast to other reports.[1114] Previous studies demonstrated an increased risk of macrocytosis, low serum and/or CSF vitamin B 12 levels, raised plasma homocysteine, and raised unsaturated R-binder capacity in MS

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High cortisol levels can also cause you to overeat, which can lead to weight gain and lowered testosterone

It severely compromises it