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Iron response element-binding protein 2 (IREB2), citrate synthase (CS), ATP synthase F0 complex subunit C3 (ATP5G3), acyl-CoA synthetase family member 2 (ACSF2), tetratricopeptide repeat domain 35 (TTC35), and ribosomal protein L8 (RPL8) are the six genes that, at the molecular level, are upregulated during ferroptosis [6]

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[Abstract]2026 Aug 1:251:229-242

Besides, some studies had shown that in sepsis-induced ARDS, the degree of neutrophil apoptosis is inversely proportional to the disease severity, and the delay of neutrophil apoptosis will aggravate lung tissue injury (99)

[48] reported that the cell surface localization of SLC7A11 can also be regulated by, e.g., the EGF receptor (EGFR), whose interaction with SLC7A11 can maintain its localization on the plasma membrane