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Consistent with these findings, an earlier murine study showed that the uncoupling of the peripheral clocks from the control of the central clock only occurred when mice had no access to food during the active phase 14

Nitric oxide modulation represents another critical mechanism particularly relevant to GERD

reported that GPX3 protein levels in ALS model rats carrying the mutant superoxide dismutase-1 (SOD1) H46R initially increased during the pre-symptomatic stage but decreased as the disease progressed [187]

MDA is a marker of LP and directly indicates the level of LP and ROS (Samad et al., 2019)

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