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Since peptides are found throughout the body, it is no surprise that when disordered, they can create ripples of effects across multiple systems

Inverse Association Between Serum Vitamin B12 Concentration and Obesity Among Adults in the United States Obesity in children and adolescents was associated with an increased risk of low vitamin B(12) concentration

Insulin is a peptide

If you are deficient in vitamin B12, then the injections are very effective at raising your blood levels

(1993) Insulin-like growth factor I stimulates lipid oxidation, reduces protein oxidation, and enhances insulin sensitivity in humans