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Solution: Use a low-and-slow approach

DED is associated with an imbalance in Th17/Treg cells, leading to increased Th17 polarization and secretion of pro-inflammatory cytokines like IL-17, causing epithelial damage (Ratay et al., 2017)

doi: 10.1016/j.bcp.2020.114201 53 ChenL.TianX.ZhangL.WangW.HuP.MaZ.et al

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