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2018;11(530):eaao4617

10.1186/s12711-015-0139-z 11 DanecekP.AutonA.AbecasisG.AlbersC

After treatment with LNP, TM-LNP, or TL-LNP at 0.5 g mL 1 of mRNA in serum-free medium for 12 h

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Avoid taking high-dose B6 supplements without consulting your doctor: While the daily upper limit is set at 100 mg pyridoxine, there have been reported cases of pyridoxine-induced neuropathy in people taking 25 to 50 mg per day for longer than six months