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It outlines the multifaceted anticancer mechanisms of bioactive compoundssuch as polyphenols, carotenoids, omega-3 fatty acids, phytosterols, alkaloids, isothiocyanates, polysaccharides, phenolic acids, flavonols, and amide-bearing compoundswhich include antioxidant and anti-inflammatory activities, induction of apoptosis and autophagy, modulation of the tumor microenvironment, interference with cell cycle regulation and signaling pathways, and regulation of cancer-related microRNA expression

Given the strong association between glutathione depletion and the progression of mitochondrial diseases, dietary supplements with the potential to increase intracellular glutathione reserves have been the subject of much research in recent years [11]

European Journal of Pharmacology, 732, 97-104

doi: 10.1172/JCI2466

Liposomal formulation with phosphatidylcholine largely solves this and makes oral supplementation clinically relevant