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Sci Rep 8:6881

S33, the expression of GCL decreased in a concentration-dependent manner after NSBSO treatment for 9 h

As IDO1 and TDO2 are the key enzymes associated with Trp-catabolism, we examined the levels of IDO1-associated Trp-catabolite Kynurenine (KYN) in the intact, OVX and OVX+E2 groups of animal plasma

While the higher concentration delivers greater healing potential, it requires careful medical oversight to ensure proper dosing, administration timing, and protocol duration

Excessive ROS production, often due to inefficient electron transport chain (ETC) function, can damage mtDNA 256 and disrupt the proper folding of mitochondrial proteins, thereby initiating the unfolded protein response (UPRmt) in mitochondria