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in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )

Theres also interest in its anti-aging benefits, since boosting NAD+ and improving metabolism can have broad positive effects on health

These include: Improved energy Weight loss Improved capacity to exercise Metabolic homeostasis The potential to boost longevity Are there side effects

Researchers are accordingly advised to refrain from administering 5-amino-1MQ indefinitely

The study also developed and validated analytical methods for detecting AOD9604 and its metabolites in biological samples, providing a framework for anti-doping testing