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1158 Trimetazidine, a drug that restricts FAO by blocking the enzyme 3-ketoacyl-CoA thiolase while simultaneously promoting glucose oxidation, 1161 not only improves the cardiac energy supply but also may regulate cardiac function by reducing systemic resting energy expenditure

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PZ: Writing original draft, Writing review & editing

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Others received therapeutic (14.3 mg/kg or 28.6 mg/kg) and supra-therapeutic CGV doses (1000, 2000 or 3000 mg/kg) body weight per oral respectively