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Sample collection, transcriptome sequencing, and data quality control Sample Collection: Three female BALB/c nude mice (8 weeks old, weighing an average of 24 3 grams) were obtained from Vitens Co., Ltd., Beijing, China

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Inflammatory cell activation can also cause relative local oxygen deficiency, triggering hypoxia-induced factors to promote the release of proangiogenic factors and causing compensatory capillary proliferation to adapt to tissue metabolic demands (Pugh and Ratcliffe, 2003)

However, a broader scoping review found that tDCS reduced perceived pain in five out of six studies involving cancer patients, with the sole negative result corresponding to a single-session intervention (114)