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In mitochondrial dysfunction, increased anaerobic glycolysis causes excess amounts of pyruvate that accumulate and is converted into lactate

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It's pointless to load in the off-season, then have your muscle stores decline if the supplement is stopped many months before a key event, such as an ultra marathon or long-distance triathlon or sportive

The most comprehensive Cochrane review of evidence on the subject found that increasing EPA and DHA has little or no effect on cardiovascular events (eg heart attack) or death (Abdelhamid et al., 2020)

[Google Scholar] 44.Monardo P., Lacquaniti A., Campo S., Bucca M., Casuscelli di Tocco T., Rovito S., Ragusa A., Santoro A