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Homocysteine, vitamin B metabolites, dopamine-substituting compounds, and symptomatology in Parkinsons disease: clinical and therapeutic considerations

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Some, like Copaxone, are FDA-approved

Possible signs of low Vitamin B12 may include: Fatigue or low energy Weakness Numbness or tingling sensations Difficulty walking or balance issues Mood changes Decreased appetite Digestive symptoms A smooth, tender tongue These symptoms can also be caused by other health conditions, so it is important to speak with a healthcare provider if you have ongoing symptoms or concerns about Vitamin B12 deficiency

Similar to the results showing improved vascularization upon co-delivery of VEGF and PDGF, PLG scaffolds could be developed that deliver Qk (the VEGF mimic) followed by PAB2-1c (the PDGF mimic) or T7 (Ang1 mimic)