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Individually, cytosine, dCTP, guanosine, cystine, and Kyn were the most increased while cysteine was the most depleted metabolite in lupus PBL (Fig

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doi: 10.1016/j.clnesp.2020.01.005 61 ShenHRXuXYeDLiXL

Some animal experiments also showcase a 54% increase in IGF-I and reduced loss of muscle strength loss in drug-induced catabolic conditions [18, 19]