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In certain cases, its consumption can elevate cortisol and adrenaline, inducing a stress-like response

[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Ivashkiv L.B., Donlin L.T

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This mitochondrial fission triggers an upregulation of CHAC1/BOTCH through the transcription factor NRF2 and ROS signaling, which in turn inhibits stem cell self-renewal and promotes cell differentiation ( 2.4.1 The antagonistic roles of CHAC1 and CHAC2 in stem cell regulation The function of CHAC1 is further refined by its competitive interaction with its homolog, CHAC2

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