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Key Points Reactive oxygen species (ROS) include superoxide, hydrogen peroxide, singlet oxygen, ozone, hypohalous acids and organic peroxides

For people with moderate to severe active IBD, corticosteroids include: Prednisone (brand name: Deltasone) Methylprednisolone (brand name: Medrol) Hydrocortisone (brand name: Cortef, Cortril, Hydrocortone) Budesonide (brand names: Entocort EC, Uceris) Budesonide is part of a new class of corticosteroids called nonsystemic steroids because they target the intestine rather than the whole body

Topical treatment Palmitoyl tetrapeptide-20 and melitane are biomimetic peptides that act as agonists of -melanocyte-stimulating hormone (-MSH) and, together with its melanocortin-1 receptor (MC1R), regulate pigment production in hair

The CCR2(+) macrophage subset promotes pathogenic angiogenesis for tumor vascularization in fibrotic livers

DNMT3a-dermatopontin axis suppresses breast cancer malignancy via inactivating YAP