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The discovered BV levels that inhibit cancer cells may be inadequate to be considered in systemic-therapy without substantial adverse effects

Those S-100 + , GDNF + , or BDNF + cells but not co-expressing human nuclei might be host Schwann cells with an injury-induced repair phenotype characterized by enhanced proliferative, migratory, and invasive capabilities [5, 56], which might have migrated through the damaged epineural barrier to the perineural areas

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[8] One such potential pathway involves the activation of phospholipase C (PLC), which researchers suggest may lead to the release of inositol triphosphate (IP3) and diacylglycerol (DAG)