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With the number to date of known intestinal membrane transporters, ion channels, and surface receptors that facilitate transport of the above-named molecules and structures from the intestinal lumen identified directly or indirectly into the systemic circulation estimated at 100 or more, the intestinal barrier is thus composed of numerous components and transport mechanisms, all regulated by bioactive molecules and by neurohormonal signaling in response to physiologic and pathologic stimuli

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With ongoing research, its potential applications in treating sleep disorders, depression, and stress-related conditions make DSIP an exciting candidate in neuroregulatory studies (2)

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[159] Another plant containing substantial amounts of L-DOPA is Vicia faba , the plant that produces fava beans (also known as "broad beans")