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Soluble fibers like psyllium, glucomannan, and inulin create a gel-like matrix in the gut that slows nutrient absorption and triggers incretin hormone secretion, including GLP-1

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Tesamorelin (2 mg/day) demonstrated reductions in trunk fat and visceral adipose tissue in HIVassociated lipodystrophy trials [3] [9]

Finally, additional proteins have emerged as particularly promising targets