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Laboratory research demonstrates interactions with specific molecular pathways in experimental models

In SURMOUNT-1, 72 weeks of tirzepatide induced mean WL of 1622.5% in people without diabetes compared to 2.4% with placebo, with no sign of the weight plateauing, suggesting that there may be further WL with long-term use [46]

These contraindications exist regardless of whether pyridoxine is included in the formulation

Peptides of this class are generally kept refrigerated and protected from light

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