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Nanoparticle size and shape strongly influence SPR behavior

10.1155/2017/7018393 63 NishinoH.KitagawaK.FujikiH.IwashimaA

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Based on the point system, average delay to diagnosis was 833 days for two points (n=20, 12.3%), 1366 days for 3 points (n=99, 55.2%), 472 days for 4 points (n=39, 23.9%) and 106 days for 5 points (n=13, 8%)

In summary, while systemic IV DFO is invasive and non-specific for brain delivery for chronic brain iron overload, it may have potential applications for immediate effect and is useful in acute neurological damage where iron is rapidly released and accessible (e.g., acute iron poisoning or ICH)