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Acetazolamide-Loaded pH-Responsive Nanoparticles Alleviating Tumor Acidosis to Enhance Chemotherapy Effects

Vitamin D is a fat-soluble vitamin, while vitamin B12 is water-soluble

doi: 10.1016/j.etap.2016.09.003

Glutathione neutralizes these molecules

Although these methods avoid reliance on reactive oxygen species, the high temperatures required may damage surrounding cells, and the emergence of heat-resistant bacteria poses additional challenges