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Inflammopharmacol 23 , 329336 (2015)

Its regulation is also different from that of NRF2, which is mainly regulated by N-glycosylase 1 (NGLY1) and DNA loss inducer 1 homolog 2 (DDI2) [13, 14]

A study reported the DOX effects based on the concentrations, at low concentrations DOX dose (o.51 M) causes the alterations in structural proteins (includes sarcomeric myosin, nuclear lamina), plasma membrane blebbing (causes change in cell shape), and mitochondrial depolarization and fragmentation