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[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C, Turner JR

A., Teaima, M

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Further to this point, BRAF V600E -mutated PA are prevalent in diencephalic areas in particular in unresectable hypothalamic/optic pathway PA, in contrast to KIAA1549-BRAF fusion-positive PA, which are prevalent in the cerebellum ( V600E is more frequently associated with non-progression, and KIAA1549-BRAF fusion was more common in progressive tumors ( BRAF-mutated diencephalic LGGs rarely present malignant transformation, but because they are usually unresectable, novel targeted therapy is strongly warranted