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The activated NLRP3 inflammasome not only maintains myocardial interstitial inflammatory infiltration, but its induced proinflammatory factors, such as interleukin (IL)-18 and IL-1, also activate profibrotic growth factors and promote the deposition of collagen and development of a profibrotic population of fibroblasts (46)

Sci Rep 2 , 566 (2012)

Johnson Mary R

Specifically, mTORC1 stimulates the expression of glycolytic enzymes by upregulating HIF-1 through the transcription factor Forkhead box K1, thereby promoting glycolysis rather than OXPHOS

ISO/IEC 17025 is an internationally recognized quality standard for testing laboratories and supports analytical accuracy, reproducibility, traceability, and validated testing methods