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One individual per group was euthanized before addressing the next animal in each group to render differences arising from the time of day at euthanization (e.g., cecal mass changes resulting from differences in time post-food consumption) comparable across all groups

The form of cobalamin used in most nutritional supplements and fortified foods, cyanocobalamin, is readily converted to 5-deoxyadenosylcobalamin and methylcobalamin in the body

compromised vials should be discarded according to local disposal regulations

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A dose of 100 mcg daily for 6 or 7 days should be administered by intramuscular or deep subcutaneous injection