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Protective effects have also been observed in models of NSAID-induced gastrointestinal damage, ethanol-induced gastric lesions, and stress-induced ulceration

, PCT

Handling & Preparation Reconstitute using bacteriostatic water per laboratory protocol Use only trained professionals Follow institutional research and safety standards Storage Instructions To preserve potency and stability: Store lyophilized vials in a cool, dry environment Refrigerate reconstituted solutions at 28C Protect from heat, light, and moisture Avoid repeated freezethaw cycles Possible Observations in Research Settings Reported observations may include: Mild redness at administration site Temporary dizziness or headache Transient nausea All findings should be documented and evaluated within controlled research environments

Mouse treatment For all experimental procedures, Tbx1 + / and WT mice were injected intraperitoneally with vB12 dissolved in PBS 20 mg/kg (stored away from light) or with PBS, twice a week for 4 wk starting at 4 wk of age

Human tolerance development remains understudied