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Aggregation is often irreversible, so discard the preparation and start again

A shortage of B12 can cause anaemia and neurological damage

Without adequate intrinsic factor, only approximately 1% of dietary B12 can be absorbed through passive diffusion , compared to the normal active transport mechanism which is far more efficient

For nausea, smaller meals, eating more slowly, and avoiding heavy or high-fat foods, especially early in treatment, are often helpful

Folate deficiency In the case of a folate deficiency, the entire folate cycle comes to a standstill with corresponding consequences on the methionine cycle and the biopterin cycle