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Plates were kept at 37 C in a humidified incubator in the presence of 5% CO 2

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The formulations were also investigated for their potential for hair growth and hair follicle viability in cases of secondary alopecia

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To test the possible increase in potency of the two drugs when given simultaneously, we injected a total volume of 4 ml of combined doses of L838,417 and CLP257 in a fixed dose ratio of \([{\mathrm{L 838,417]/[{\mathrm{CLP 257]\) = 1:55, given the relative EC50s of the two drugs calculated from the respective dose response curves with a priori assumption on the collapse at high doses of L838,417 (Fig