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Indeed, a pilot study on young patients with ALL suffering from chemo-induced liver toxicity found that treatment with milk thistle led to a "trend towards significant reductions in liver toxicity."24 The researchers state that future studies are needed to zero in on the ideal dosage and duration of treatment, but their findings suggest that milk thistle may be a promising intervention for acute liver injury secondary to chemo

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The data generated during this phase help define the dose range that may be explored in subsequent studies and contribute to understanding exposure-response relationships, pharmacokinetic behavior and safety considerations associated with the investigational compound

I give 5 grams with any medication, also during any time of stress

The only side effects present are for patients that are allergic to a compound found in these injections