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55 The phase 3 REDEFINE-3 trial will further assess the impact of cagrilinitide/semaglutide on major adverse cardiovascular events in people with obesity (with or without T2DM) and established CVD (clinical trial number NCT05669755

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It achieves this by modulating MMPs and by attracting immune cells and endothelial cells to injury sites

Among these, long-term use of macrolide antibiotics has been proven to reduce acute exacerbation occurrence risk, but this treatment strategy also brings potential problems of antibiotic resistance and drug adverse reactions ( DPP1 inhibitors have clear potential advantages in bronchiectasis treatment

Their method of delivery through the nasal passage offers a simple, needle-free solution that many find appealing