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Eicher, L

Eide, M., Rusten, M., Male, R., Jensen, K

To achieve a plasma level of 0.7mM (less than the 1mM used int he paper), you have to give a rat 150mg/kg/day IV, which is the equivalent of a 1451mg IV SAMe daily dose to a 60kg human, but since the oral absorption is around 5%, that's the equivalent of more than a 29,000mg daily oral dose

Kim S, Kwon J (2014) Thymosin beta 4 improves dermal burn wound healing via downregulation of receptor of advanced glycation end products in db/db mice